While the majority of the crypto market is in a slump, with ETH and BTC down 5.5% and 2.6% respectively, the DeSci juggernaut, BIO Protocol, has surged more than 20% overnight. The pump by BIO crypto has led to calls for a DeSci (Decentralized Science) revival.
The bullish price action for BIO has already had a trickle-down effect on the sector, with CoinGecko data showing the combined DeSci market cap sitting at $799 million, up 7.7% in the past 24 hours.
BIO Protocol Leads DeSci Resurgence: Best Tokens Explode Overnight?
Although BIO Protocol is the leading name within the DeSci space, its overnight surge has dragged several tokens along. VitaDAO (VITA), HairDAO (HAIR), and ValleyDao (GROW) are up 12%, 8%, and 7% respectively.
The DeSci narrative burst onto the scene in November 2024 after Ethereum co-founder Vitalik Buterin and Binance co-founder CZ attended a Decentralized Science meetup in Thailand. Both spoke highly about the sector, claiming that DeSci would be one of the next big Web3 industries to explode.
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As a result of that meetup, November resulted in a mini DeSci ‘szn’, with many tokens such as VitaDAO and ResearchCoin all exploding, before the market moved back to AI, resulting in a cooldown across the DeSci space.
However, the space has begun a revival over the past few months, with BIO Protocol following a near 90% pump over the past month. BIO launched after the November 2024 DeSci pump, and held its TGE (token generation event) in January 2025 following an undisclosed funding round led by YZi Labs (formerly Binance Labs).
Unsurprisingly, Binance proceeded to launch BIO Protocol via its launchpool protocol, whereby users staking BNB received a percentage of the token supply, before it went live on the full Binance platform.
The timing of the BIO launch was unfortunate, as crypto went on to experience a market-wide crash between January and April, causing BIO Protocol to crash by over 90%. Despite this recent bullish price action for BIO, it is still down 85% from its $0.8 all-time high at launch.
Demand for BIO is at an all-time high, as daily trading volume has exceeded $420 million, nearly 2x its current market cap of $240 million. Anytime a token’s volume outweighs its market cap, it is a good sign that the asset is undervalued and a repricing is likely.
Futures volume for BIO Protocol is also surging, with over $1 billion over the past 24 hours and nearly $600 million of that being processed on Binance.
Continued bullish price action for BIO will likely lead to another DeSci cycle, with projects such as Bitcoin Hyper (HYPER) possible beneficiaries of a surge across DeSci. HYPER is a Bitcoin Layer-2 protocol that will open up the possibility of introducing many new sectors to Bitcoin, with Decentralized Science one of many candidates.
Could Bitcoin Hyper (HYPER) Bring DeSci to Bitcoin?
Bitcoin Hyper (HYPER) could be the missing piece that finally allows the Bitcoin ecosystem to realize its full potential. Over the weekend, HYPER secured a landmark $10 million in ICO funding, highlighting that it is one of the most sought-after presale tokens in 2025.
The HYPER team’s goal is to bring a complete end-to-end ecosystem of products to the Bitcoin mainnet. Along with DeFi, GameFi, and NFTs, DeSci is another industry that could be brought to Bitcoin with the help of Bitcoin Hyper.
A DeSci launchpad could be built on Bitcoin Hyper, allowing a whole ecosystem of DeSci tokens to be birthed onto the Bitcoin mainnet.
HYPER is intelligently utilizing the Solana Virtual Machine (SVM) for its Layer-2 protocol to achieve these lofty goals. When bringing its L2 infrastructure to Bitcoin, HYPER will benefit from the low fees and super-fast speeds associated with Solana.
Bitcoin Hyper is building with innovative rollup technology. The team’s recent announcement of full integration with the SVM as the execution layer on HYPER, coupled with the utilization of rollups, will facilitate fast transactions, low fees, and real-time execution without changing Bitcoin’s tried and tested core base layer.
Investors can also stake their HYPER tokens for a generous 105% APY in rewards, providing a perfect opportunity for passive income while waiting for the Bitcoin Hyper ICO to conclude.
Just under 17 hours remain before the HYPER presale moves onto its next price stage, meaning its current price of $0.012745 will be gone for good.
For the latest updates on all things HYPER, join the community on Telegram and X.
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